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Side by side

IGF-1 LR3 vs Ipamorelin

Both are discussed for muscle & performance. What this site records about each, side by side. Every figure is on the compound's own page with the source it came from.

IGF-1 LR3 and Ipamorelin compared on what BioAlmanac records.
 IGF-1 LR3Ipamorelin
What it isA modified insulin-like growth factor engineered to last far longer in the body than the natural hormone. It can cause hypoglycaemia, which makes it the most acutely dangerous compound on this site.A selective growth hormone secretagogue that prompts a short pulse of GH release. Widely used, and supported almost entirely by early pharmacology rather than outcome trials.
EvidenceHow much human evidence exists, not how well it works.PreclinicalEarly human trials
Regulatory statusReviewed 2026-08-16Not approved for human use in any jurisdiction, and never studied in a human trial. Recombinant IGF-1 itself (mecasermin) is approved for severe primary IGF-1 deficiency, and its labelling carries an explicit hypoglycaemia warning. That warning is the closest thing to clinical safety information this class has.Not approved for human use in the United States for any indication. The FDA has identified ipamorelin as a substance raising concerns for use in compounded preparations. Material sold online is a research chemical.
RoutesSubcutaneous, IntramuscularSubcutaneous
Half-life24 hours2 hours
Cheapest per mgVials only, read from vendors' own listings and dated on the price index.$32.50/mg$2.00/mg
Median per mg$79.00/mg$5.50/mg
Vendors with a price3254
Storage once mixedRefrigerated at 2–8 °C. Do not freeze once mixed. Larger proteins are less forgiving of temperature swings than short peptides.Refrigerated at 2–8 °C. Do not freeze once mixed.

Compare two other compounds · The full price index

This page is educational. It describes what published research reports, not what you should do. Peptides discussed here are largely not approved for human use, and nothing on BioAlmanac is medical advice. Nothing here ranks these two against each other. A table can show that one has more human evidence behind it or costs less per milligram; neither of those is a recommendation, and the right comparison for any person is one their doctor makes with them.