Side by side
L-Carnitine vs Orforglipron
Both are discussed for weight loss. What this site records about each, side by side. Every figure is on the compound's own page with the source it came from.
| L-Carnitine | Orforglipron | |
|---|---|---|
| What it is | An essential cofactor for burning fat, and not the step that limits it. Approved for genuine carnitine deficiency; sold by injection for weight loss on weak evidence. | The first GLP-1 pill that is a true small molecule. Approved in April 2026, and taken any time of day with no food or water restrictions. |
| EvidenceHow much human evidence exists, not how well it works. | Approved | Approved |
| Regulatory statusReviewed 2026-08-18 | Levocarnitine is an FDA-approved prescription medicine for primary and secondary carnitine deficiency. Oral carnitine is also sold as a dietary supplement. Injectable carnitine for weight loss is not an approved use. | Approved by the FDA on 1 April 2026 as Foundayo, for chronic weight management in adults with obesity, or overweight with a weight-related condition. The first non-peptide, small-molecule GLP-1 receptor agonist approved for weight loss. |
| Routes | Oral, Intramuscular, Intravenous | Oral |
| Half-life | 17.4 hours | 30 hours |
| Cheapest per mgVials only, read from vendors' own listings and dated on the price index. | $0.01/mg | $40.00/mg |
| Median per mg | $0.08/mg | $40.00/mg |
| Vendors with a price | 13 | 1 |
| Storage once mixed | Injectable carnitine is supplied as a solution, not a powder. | Not applicable. This is a tablet. |
Compare two other compounds · The full price index
This page is educational. It describes what published research reports, not what you should do. Peptides discussed here are largely not approved for human use, and nothing on BioAlmanac is medical advice. Nothing here ranks these two against each other. A table can show that one has more human evidence behind it or costs less per milligram; neither of those is a recommendation, and the right comparison for any person is one their doctor makes with them.