Side by side
LL-37 vs TB-500
Both are discussed for healing & recovery. What this site records about each, side by side. Every figure is on the compound's own page with the source it came from.
| LL-37 | TB-500 | |
|---|---|---|
| What it is | The human body's own antimicrobial peptide, part of innate immunity. Genuinely important biology, and implicated in causing disease as often as treating it. | A synthetic fragment of thymosin beta-4, a naturally occurring protein involved in cell migration and tissue repair. Animal evidence only. |
| EvidenceHow much human evidence exists, not how well it works. | Early human trials | Preclinical |
| Regulatory statusReviewed 2026-08-16 | Not approved for human use in any jurisdiction. A synthetic version has reached small phase 2 study as a topical wound treatment. Injected LL-37 has never been studied in a human trial, and is sold only as a research chemical. | Not approved for human use in the United States. Sold only as a research chemical, with no manufacturing standard behind that label. |
| Routes | Topical, Subcutaneous | Subcutaneous, Intramuscular |
| Half-life | Not recorded | 2 hours |
| Cheapest per mgVials only, read from vendors' own listings and dated on the price index. | $3.40/mg | $1.20/mg |
| Median per mg | $11.60/mg | $6.00/mg |
| Vendors with a price | 25 | 40 |
| Storage once mixed | Refrigerated at 2–8 °C. Do not freeze once mixed. LL-37 adsorbs to plastic, so a substantial fraction can be lost to the walls of the container. Glass is preferable. | Refrigerated at 2–8 °C. Do not freeze once mixed. |
Compare two other compounds · The full price index
This page is educational. It describes what published research reports, not what you should do. Peptides discussed here are largely not approved for human use, and nothing on BioAlmanac is medical advice. Nothing here ranks these two against each other. A table can show that one has more human evidence behind it or costs less per milligram; neither of those is a recommendation, and the right comparison for any person is one their doctor makes with them.