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Tesamorelin / Ipamorelin vs Tirzepatide

Both are discussed for weight loss. What this site records about each, side by side. Every figure is on the compound's own page with the source it came from.

Tesamorelin / Ipamorelin and Tirzepatide compared on what BioAlmanac records.
 Tesamorelin / IpamorelinTirzepatide
What it isAn approved GHRH analogue paired with a ghrelin agonist. Sold at three different splits, which matters more here than in most blends.A once-weekly dual agonist that activates both the GIP and GLP-1 receptors, approved for type 2 diabetes and for weight management.
EvidenceHow much human evidence exists, not how well it works.PreclinicalApproved
Regulatory statusReviewed 2026-08-25Tesamorelin is approved by the FDA for HIV-associated lipodystrophy. Ipamorelin is approved nowhere, and the mixture is approved nowhere. Sold as a research chemical at several ratios.Approved by the FDA as a prescription medicine for type 2 diabetes and for chronic weight management. Material sold as a research chemical is not the approved product and is not legal to sell for human use.
RoutesSubcutaneousSubcutaneous
Half-lifeNot recorded120 hours
Cheapest per mgVials only, read from vendors' own listings and dated on the price index.$3.44/mg$1.00/mg
Median per mg$6.54/mg$3.17/mg
Vendors with a price2333
Storage once mixedRefrigerated at 2–8 °C and used within about 30 days. A blend cannot be split. A contaminated vial takes every component with it.Refrigerated at 2–8 °C. Do not freeze. Discard if cloudy or discoloured.

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This page is educational. It describes what published research reports, not what you should do. Peptides discussed here are largely not approved for human use, and nothing on BioAlmanac is medical advice. Nothing here ranks these two against each other. A table can show that one has more human evidence behind it or costs less per milligram; neither of those is a recommendation, and the right comparison for any person is one their doctor makes with them.