Side by side
Tesamorelin vs Testosterone (TRT)
Both are discussed for muscle & performance. What this site records about each, side by side. Every figure is on the compound's own page with the source it came from.
| Tesamorelin | Testosterone (TRT) | |
|---|---|---|
| What it is | A GHRH analogue approved by the FDA for reducing excess visceral fat in HIV-associated lipodystrophy. The only compound in this category with completed phase 3 trials. | Not a peptide, and the most consequential thing on this site. Approved replacement therapy for diagnosed hypogonadism — a Schedule III controlled substance — and something that will make you infertile while you take it. |
| EvidenceHow much human evidence exists, not how well it works. | Approved for another indication | Approved |
| Regulatory statusReviewed 2026-08-12 | Approved by the FDA as a prescription medicine for reducing excess visceral abdominal fat in adults with HIV-associated lipodystrophy. It is not approved for body composition, athletic performance or anti-ageing use, and material sold as a research chemical is not the approved product. | Approved by the FDA and EMA for diagnosed male hypogonadism, and a Schedule III controlled substance in the United States. Labelling was updated in 2025 following the TRAVERSE trial. Not approved for age-related decline in testosterone without a confirmed diagnosis. |
| Routes | Subcutaneous | Intramuscular, Subcutaneous, Topical |
| Half-life | 0.4 hours | 192 hours |
| Cheapest per mgVials only, read from vendors' own listings and dated on the price index. | $2.35/mg | Not recorded |
| Median per mg | $7.00/mg | Not recorded |
| Vendors with a price | 49 | Not recorded |
| Storage once mixed | Refrigerated at 2–8 °C. The approved product is intended for use shortly after reconstitution rather than stored for weeks. | Nothing to reconstitute. A multi-dose vial is good until its expiry if the stopper is cleaned before each draw. |
Compare two other compounds · The full price index
This page is educational. It describes what published research reports, not what you should do. Peptides discussed here are largely not approved for human use, and nothing on BioAlmanac is medical advice. Nothing here ranks these two against each other. A table can show that one has more human evidence behind it or costs less per milligram; neither of those is a recommendation, and the right comparison for any person is one their doctor makes with them.