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Bioalmanac

Adipotide

FTPP · Prohibitin-targeting peptide · CKGGRAKDC-GG-D(KLAKLAK)2

Preclinical

Status reviewed 16 Aug 2026

A peptide designed to kill the blood supply feeding fat tissue. It worked in monkeys, and it damaged their kidneys.

Storage

Freeze-dried powder
Refrigerated at 2–8 °C, protected from light.
After mixing
Refrigerated at 2–8 °C. Do not freeze once mixed.
Long-term, frozen
Unopened powder is stable at −20 °C or colder.

Reconstitution — 10 mg vial, 500 mcg dose

On a 1 mL U-100 syringe. Check every figure against your own vial before drawing.

Water addedConcentrationVolume to drawUnitsDoses per vial
1 mL10 mg/mL0.05 mL5 units20
2 mL5 mg/mL0.1 mL10 units20
3 mL3.333 mg/mL0.15 mL15 units20
5 mL2 mg/mL0.25 mL25 units20

Dose ranges reported in sources

Descriptions of what sources report, not recommendations.

GoalRangeFrequencySource
Primate study protocol430 mcgOnce daily for 28 daysPublished review
Commonly described community protocol500–1000 mcgDaily for a course of two to four weeksCommunity practice

When to stop

  • Any reduction in urine output, swelling in the legs or face, or foamy urine. All are possible signs of kidney injury. Stop and seek medical assessment.
  • Rising creatinine or falling eGFR on bloodwork. Kidney damage is usually silent before it is symptomatic, which is why the bloodwork rather than how you feel is the signal.
  • Nausea, vomiting or an inability to keep fluids down. Dehydration compounds the renal risk.
  • Any allergic response: rash, hives, facial swelling or difficulty breathing. Seek urgent care.
  • An injection site that ulcerates or does not heal.

Not approved anywhere. A phase 1 trial in obese prostate cancer patients was initiated; no result establishing safety or efficacy has been published, and development has not continued. Sold only as a research chemical.

Arithmetic on values you enter. Not medical advice. Not reviewed by a clinician. · bioalmanac.com/peptides/adipotide

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