Bioalmanac
Afamelanotide
Melanotan I · MT-1 · Scenesse (brand) · Nle4-D-Phe7-α-MSH
The approved member of the melanotan family. Same idea as melanotan II, taken through a full regulatory process, and the contrast between them is instructive.
Storage
- Freeze-dried powder
- Refrigerated at 2–8 °C, protected from light.
- After mixing
- Refrigerated at 2–8 °C. Do not freeze once mixed.
- Long-term, frozen
- Unopened powder is stable at −20 °C or colder.
Reconstitution — 10 mg vial, 500 mcg dose
On a 1 mL U-100 syringe. Check every figure against your own vial before drawing.
| Water added | Concentration | Volume to draw | Units | Doses per vial |
|---|---|---|---|---|
| 1 mL | 10 mg/mL | 0.05 mL | 5 units | 20 |
| 2 mL | 5 mg/mL | 0.1 mL | 10 units | 20 |
| 3 mL | 3.333 mg/mL | 0.15 mL | 15 units | 20 |
| 5 mL | 2 mg/mL | 0.25 mL | 25 units | 20 |
Dose ranges reported in sources
Descriptions of what sources report, not recommendations.
| Goal | Range | Frequency | Source |
|---|---|---|---|
| Approved regimen for erythropoietic protoporphyria | 16000 mcg | One implant every two months | Clinical trial |
| Commonly described community protocol for injectable powder | 500–1000 mcg | Daily during a loading phase, then weekly | Community practice |
When to stop
- Any mole that changes in size, shape, colour or border, or that bleeds or itches. See a dermatologist promptly.
- Any new pigmented lesion.
- Any allergic response: rash, hives, facial swelling or difficulty breathing. Seek urgent care.
- Persistent nausea or headache that does not settle.
- An implant site that becomes hot, spreading or produces pus.
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