Bioalmanac
AICAR
Acadesine · AICA riboside · 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside · AICA-riboside
A nucleoside, not a peptide. About fifteen hundred people have been given it intravenously in a heart surgery trial, where it did nothing. Banned in sport since 2009 on the strength of a mouse study.
Storage
- Freeze-dried powder
- Refrigerated, protected from light.
- After mixing
- Refrigerated. A small molecule rather than a peptide, so the usual peptide stability rules do not transfer.
- Long-term, frozen
- Stable frozen as a dry powder.
Dose ranges reported in sources
Descriptions of what sources report, not recommendations.
| Goal | Range | Frequency | Source |
|---|---|---|---|
| Commonly described community protocol | 50000–100000 mcg | Daily | Community practice |
When to stop
- Joint pain or swelling suggesting gout.
- Persistent unexplained fatigue or muscle weakness.
- Any allergic response: rash, hives, facial swelling or difficulty breathing. Seek urgent care.
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