Bioalmanac
ARA-290
Cibinetide · Erythropoietin helix B surface peptide · pHBSP
An eleven-amino-acid fragment of erythropoietin that keeps the tissue-repair signalling and drops the blood-thickening. Studied properly in nerve damage, with a published randomised trial.
Storage
- Freeze-dried powder
- Refrigerated at 2–8 °C, protected from light.
- After mixing
- Refrigerated at 2–8 °C. Do not freeze once mixed.
- Long-term, frozen
- Unopened powder is stable at −20 °C or colder.
Reconstitution — 5 mg vial, 4000 mcg dose
On a 1 mL U-100 syringe. Check every figure against your own vial before drawing.
| Water added | Concentration | Volume to draw | Units | Doses per vial |
|---|---|---|---|---|
| 1 mL | 5 mg/mL | 0.8 mL | 80 units | 1.3 |
| 2 mL | 2.5 mg/mL | — | Exceeds a 1 mL barrel | — |
| 3 mL | 1.667 mg/mL | — | Exceeds a 1 mL barrel | — |
| 5 mL | 1 mg/mL | — | Exceeds a 1 mL barrel | — |
Dose ranges reported in sources
Descriptions of what sources report, not recommendations.
| Goal | Range | Frequency | Source |
|---|---|---|---|
| Phase 2 protocol for small fibre neuropathy | 4000 mcg | Once daily for 28 days | Clinical trial |
| Commonly described community protocol | 1000–4000 mcg | Once daily in courses of several weeks | Community practice |
When to stop
- Any allergic response: rash, hives, facial swelling or difficulty breathing. Seek urgent care.
- An injection site that becomes hot, spreading or produces pus.
- Worsening neuropathic pain rather than improvement.
- Persistent headache that does not settle.
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