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Bioalmanac

Dihexa

N-hexanoic-Tyr-Ile-(6) aminohexanoic amide · PNB-0408

Preclinical

Status reviewed 16 Aug 2026

A small peptide reported as vastly more potent than BDNF at forming new synapses in animals. No human has been studied on it, and the potency is the concern, not the selling point.

Storage

Freeze-dried powder
Powder refrigerated at 2–8 °C, protected from light and moisture.
After mixing
In a carrier solution, refrigerated and used within weeks. Stability in DMSO or similar carriers has not been characterised.
Long-term, frozen
Powder is stable at −20 °C or colder.

Dose ranges reported in sources

Descriptions of what sources report, not recommendations.

GoalRangeFrequencySource
Commonly described community protocol5000–20000 mcgOnce daily, often in short coursesCommunity practice

When to stop

  • Any new neurological symptom: persistent headache, visual change, unusual mood change, confusion or seizure activity. Seek medical assessment.
  • Any allergic response: rash, hives, facial swelling or difficulty breathing. Seek urgent care.
  • Any new lump, unexplained weight loss or unexplained persistent pain.
  • Skin irritation where a transdermal carrier is applied.

Not approved anywhere, and never studied in a published human trial. Developed in academic research with an associated patent; no clinical development programme has reported results. Sold only as a research chemical.

Arithmetic on values you enter. Not medical advice. Not reviewed by a clinician. · bioalmanac.com/peptides/dihexa

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