Bioalmanac
Follistatin-344
FS-344 · Follistatin 344
A myostatin-blocking protein with dramatic animal results, no human trials, and a serious question over whether what is sold is the real thing.
Storage
- Freeze-dried powder
- Refrigerated at 2–8 °C, protected from light.
- After mixing
- Refrigerated at 2–8 °C, and used quickly. A large glycoprotein is far less stable in solution than a short peptide, and it will not look any different once it has lost activity.
- Long-term, frozen
- Unopened powder at −20 °C or colder. Avoid freeze-thaw cycles entirely. Each one degrades a protein of this size.
Reconstitution — 1 mg vial, 200 mcg dose
On a 1 mL U-100 syringe. Check every figure against your own vial before drawing.
| Water added | Concentration | Volume to draw | Units | Doses per vial |
|---|---|---|---|---|
| 1 mL | 1 mg/mL | 0.2 mL | 20 units | 5 |
| 2 mL | 0.5 mg/mL | 0.4 mL | 40 units | 5 |
| 3 mL | 0.333 mg/mL | 0.6 mL | 60 units | 5 |
| 5 mL | 0.2 mg/mL | 1 mL | 100 units | 5 |
Dose ranges reported in sources
Descriptions of what sources report, not recommendations.
| Goal | Range | Frequency | Source |
|---|---|---|---|
| Commonly described community protocol | 100–300 mcg | Daily for a course of 10 to 30 days | Community practice |
When to stop
- Nosebleeds, or new visible small blood vessels in the skin. These are the specific effects that halted the ACE-031 trials.
- Unusual bruising or bleeding that does not stop normally.
- Any allergic response: rash, hives, facial swelling or difficulty breathing. Seek urgent care.
- Changes in libido, menstrual cycle or testicular size, which would suggest reproductive axis effects.
- Any new lump or unexplained persistent pain.
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