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Bioalmanac

GHK-Cu

Copper peptide · Copper tripeptide-1 · Gly-His-Lys copper

Preclinical

Status reviewed 12 Aug 2026

A naturally occurring copper-binding tripeptide with a long history in topical skincare research. Injected use is not what the research studied.

Storage

Freeze-dried powder
Refrigerated at 2–8 °C, protected from light.
After mixing
Refrigerated at 2–8 °C. The solution is characteristically blue; that colour is expected and is not a fault.
Long-term, frozen
Unopened powder is stable at −20 °C or colder.

Reconstitution — 50 mg vial, 1250 mcg dose

On a 1 mL U-100 syringe. Check every figure against your own vial before drawing.

Water addedConcentrationVolume to drawUnitsDoses per vial
1 mL50 mg/mL0.025 mL2.5 units40
2 mL25 mg/mL0.05 mL5 units40
3 mL16.667 mg/mL0.075 mL7.5 units40
5 mL10 mg/mL0.125 mL12.5 units40

Dose ranges reported in sources

Descriptions of what sources report, not recommendations.

GoalRangeFrequencySource
Commonly described injected dose1000–2000 mcgOnce dailyCommunity practice
As delivered within a GLOW or KLOW blend1250–2000 mcgOnce dailyCommunity practice

When to stop

  • Signs of infection at an injection site: spreading redness, warmth, swelling, pus, or fever.
  • Any allergic response: rash, hives, facial swelling, or difficulty breathing. Seek urgent care.
  • Persistent nausea, abdominal pain or fatigue, which are among the features of copper excess.
  • Injection site reactions that intensify with each dose.

Permitted as a topical cosmetic ingredient in the United States and widely sold as such. Not approved as an injectable medicine, and injectable material is a research chemical with no manufacturing standard behind it.

Arithmetic on values you enter. Not medical advice. Not reviewed by a clinician. · bioalmanac.com/peptides/ghk-cu

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