Bioalmanac
Glutathione
GSH · Reduced glutathione · L-glutathione
The body's main antioxidant, and a poor drug. The FDA has warned specifically against the injectable skin-lightening use. That is what most of it is sold for.
Storage
- Freeze-dried powder
- Refrigerated at 2–8 °C, protected from light. Glutathione oxidises readily on exposure to air.
- After mixing
- Use promptly. The reduced form oxidises in solution, and the oxidised form is not what is wanted.
- Long-term, frozen
- Unopened powder is stable at −20 °C or colder.
Dose ranges reported in sources
Descriptions of what sources report, not recommendations.
| Goal | Range | Frequency | Source |
|---|---|---|---|
| Doses used in clinics | 600000–2400000 mcg | One to three times weekly | Community practice |
| Parkinson's disease trials | 1400000 mcg | Three times weekly by infusion | Clinical trial |
When to stop
- Any allergic response: rash, hives, facial swelling or difficulty breathing. Seek urgent care.
- Fever, chills, or an infusion site that becomes hot or starts spreading. Possible infection. Seek urgent care.
- Uneven or patchy loss of skin pigment.
- Abdominal pain or persistent nausea.
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