Bioalmanac
Gonadorelin
GnRH · LHRH · Factrel (brand) · Luteinising hormone-releasing hormone
Natural GnRH, approved as a diagnostic agent. Widely used alongside testosterone therapy on a rationale that is sound in principle and unstudied in that setting.
Storage
- Freeze-dried powder
- Refrigerated at 2–8 °C, protected from light.
- After mixing
- Refrigerated at 2–8 °C. Do not freeze once mixed. Bacteriostatic water is preferable given the multi-week dosing pattern.
- Long-term, frozen
- Unopened powder is stable at −20 °C or colder.
Reconstitution — 2 mg vial, 100 mcg dose
On a 1 mL U-100 syringe. Check every figure against your own vial before drawing.
| Water added | Concentration | Volume to draw | Units | Doses per vial |
|---|---|---|---|---|
| 1 mL | 2 mg/mL | 0.05 mL | 5 units | 20 |
| 2 mL | 1 mg/mL | 0.1 mL | 10 units | 20 |
| 3 mL | 0.667 mg/mL | 0.15 mL | 15 units | 20 |
| 5 mL | 0.4 mg/mL | 0.25 mL | 25 units | 20 |
Dose ranges reported in sources
Descriptions of what sources report, not recommendations.
| Goal | Range | Frequency | Source |
|---|---|---|---|
| Diagnostic test, the approved use | 100 mcg | A single dose, once | Clinical trial |
| Commonly prescribed alongside testosterone therapy | 100–200 mcg | Two to three times weekly, or on the same schedule as testosterone | Community practice |
When to stop
- Testicular shrinkage that continues or worsens. That is the outcome it is meant to prevent, and a sign the schedule may be suppressing rather than stimulating.
- Falling libido or morning erections beyond what the testosterone protocol explains.
- Any allergic response: rash, hives, facial swelling or difficulty breathing. Seek urgent care.
- Persistent headache, flushing or nausea after dosing.
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