Bioalmanac
IGF-1 LR3
Long R3 IGF-1 · LR3 · Long Arg3 IGF-1
A modified insulin-like growth factor engineered to last far longer in the body than the natural hormone. It can cause hypoglycaemia, which makes it the most acutely dangerous compound on this site.
Storage
- Freeze-dried powder
- Refrigerated at 2–8 °C, protected from light.
- After mixing
- Refrigerated at 2–8 °C. Do not freeze once mixed. Larger proteins are less forgiving of temperature swings than short peptides.
- Long-term, frozen
- Unopened powder is stable at −20 °C or colder.
Reconstitution — 1 mg vial, 40 mcg dose
On a 1 mL U-100 syringe. Check every figure against your own vial before drawing.
| Water added | Concentration | Volume to draw | Units | Doses per vial |
|---|---|---|---|---|
| 1 mL | 1 mg/mL | 0.04 mL | 4 units | 25 |
| 2 mL | 0.5 mg/mL | 0.08 mL | 8 units | 25 |
| 3 mL | 0.333 mg/mL | 0.12 mL | 12 units | 25 |
| 5 mL | 0.2 mg/mL | 0.2 mL | 20 units | 25 |
Dose ranges reported in sources
Descriptions of what sources report, not recommendations.
| Goal | Range | Frequency | Source |
|---|---|---|---|
| Commonly described community protocol | 20–50 mcg | Once daily | Community practice |
When to stop
- Any sign of low blood sugar: sweating, shaking, confusion, palpitations, sudden hunger, blurred vision. Take fast-acting carbohydrate immediately. If confusion or loss of consciousness occurs, this is an emergency. Call emergency services.
- Repeated hypoglycaemic episodes, even mild ones. This is the compound telling you the dose is wrong, and the next episode may not be mild.
- Any new lump, swelling or unexplained persistent pain.
- Jaw pain, difficulty swallowing, or snoring that is new. All reported with the approved recombinant product.
- Any allergic response: rash, hives, facial swelling or difficulty breathing. Seek urgent care.
- Changes in vision that do not resolve.
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