Bioalmanac
Liraglutide
Victoza (brand) · Saxenda (brand) · NN2211
The first GLP-1 analogue approved for weight loss. A daily injection, superseded by weekly semaglutide but still the best-documented compound in the class.
Storage
- Freeze-dried powder
- The approved product is a solution, not a powder. Refrigerated at 2–8 °C before first use.
- After mixing
- After first use, up to 30 days at room temperature below 30 °C or refrigerated. Protect from light and do not freeze.
- Long-term, frozen
- Never freeze. Freezing destroys it, and it cannot be used after.
Reconstitution — 18 mg vial, 3000 mcg dose
On a 1 mL U-100 syringe. Check every figure against your own vial before drawing.
| Water added | Concentration | Volume to draw | Units | Doses per vial |
|---|---|---|---|---|
| 1 mL | 18 mg/mL | 0.167 mL | 16.67 units | 6 |
| 2 mL | 9 mg/mL | 0.333 mL | 33.33 units | 6 |
| 3 mL | 6 mg/mL | 0.5 mL | 50 units | 6 |
| 5 mL | 3.6 mg/mL | 0.833 mL | 83.33 units | 6 |
Dose ranges reported in sources
Descriptions of what sources report, not recommendations.
| Goal | Range | Frequency | Source |
|---|---|---|---|
| Weight management escalation, as approved | 600–3000 mcg | Once daily, increasing by 0.6 mg each week | Clinical trial |
| Type 2 diabetes, as approved | 600–1800 mcg | Once daily | Clinical trial |
When to stop
- Severe, persistent abdominal pain, particularly radiating to the back. Possible pancreatitis. Stop and seek urgent care.
- Pain in the upper right abdomen, fever, or yellowing of the skin or eyes. Possible gallbladder disease. Seek care.
- A lump in the neck, hoarseness that does not resolve, or difficulty swallowing. Investigate before continuing.
- Vomiting severe enough that you cannot keep fluids down. Dehydration on a GLP-1 can injure the kidneys.
- Any allergic response: rash, hives, facial swelling or difficulty breathing. Seek urgent care.
- Signs of low blood sugar if you also use insulin or a sulfonylurea: sweating, shaking, confusion. Those doses usually need reducing.
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