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Bioalmanac

Melanotan II

MT-2 · MT-II · Melanotan 2

Preclinical

Status reviewed 12 Aug 2026

A melanocortin agonist that darkens skin by stimulating melanin production. Carries the most serious dermatological concern of anything on this site.

Storage

Freeze-dried powder
Refrigerated at 2–8 °C, protected from light.
After mixing
Refrigerated at 2–8 °C. Do not freeze once mixed.
Long-term, frozen
Unopened powder is stable at −20 °C or colder.

Reconstitution — 10 mg vial, 250 mcg dose

On a 1 mL U-100 syringe. Check every figure against your own vial before drawing.

Water addedConcentrationVolume to drawUnitsDoses per vial
1 mL10 mg/mL0.025 mL2.5 units40
2 mL5 mg/mL0.05 mL5 units40
3 mL3.333 mg/mL0.075 mL7.5 units40
5 mL2 mg/mL0.125 mL12.5 units40

Dose ranges reported in sources

Descriptions of what sources report, not recommendations.

GoalRangeFrequencySource
Loading, commonly described250–500 mcgDaily until the desired pigmentation is reachedCommunity practice
Maintenance, commonly described500–1000 mcgOne to two times weeklyCommunity practice

When to stop

  • Any mole that changes in size, shape, colour or border, or that bleeds or itches. Stop and see a dermatologist promptly. This is the specific risk this compound carries.
  • Any new pigmented lesion.
  • Severe or persistent nausea and vomiting.
  • Any allergic response: rash, hives, facial swelling or difficulty breathing. Seek urgent care.
  • An erection lasting more than four hours is a medical emergency — seek immediate care.

Not approved for human use in any jurisdiction. Multiple national medicines regulators have issued public safety warnings specifically about melanotan products, citing unregulated manufacture and dermatological risk. Sold only as a research chemical.

Arithmetic on values you enter. Not medical advice. Not reviewed by a clinician. · bioalmanac.com/peptides/melanotan-2

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