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Bioalmanac

Orforglipron

Foundayo (brand) · LY3502970

Approved

Status reviewed 18 Aug 2026

The first GLP-1 pill that is a true small molecule. Approved in April 2026, and taken any time of day with no food or water restrictions.

Storage

Freeze-dried powder
Tablets at room temperature, in the original packaging.
After mixing
Not applicable. This is a tablet.

Dose ranges reported in sources

Descriptions of what sources report, not recommendations.

GoalRangeFrequencySource
Approved escalation for weight management6000–36000 mcgOnce daily, escalating over several monthsClinical trial

When to stop

  • Severe, persistent abdominal pain, particularly radiating to the back. Possible pancreatitis. Seek urgent care.
  • Pain in the upper right abdomen, fever, or yellowing of the skin or eyes.
  • A lump in the neck, hoarseness that does not resolve, or difficulty swallowing.
  • Vomiting severe enough that you cannot keep fluids down.
  • Any allergic response: rash, hives, facial swelling or difficulty breathing. Seek urgent care.

Approved by the FDA on 1 April 2026 as Foundayo, for chronic weight management in adults with obesity, or overweight with a weight-related condition. The first non-peptide, small-molecule GLP-1 receptor agonist approved for weight loss.

Arithmetic on values you enter. Not medical advice. Not reviewed by a clinician. · bioalmanac.com/peptides/orforglipron

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