Bioalmanac

P21

P021 · Cel-N-adamantyl Ac-DGGL-NH2 · CNTF-derived peptide

Preclinical

Status reviewed 18 Aug 2026

A tetrapeptide derived from a nerve growth factor, engineered to reach the brain. Real academic research, entirely in mice.

Storage

Freeze-dried powder: Refrigerated at 2–8 °C, protected from light.
After mixing: Refrigerated at 2–8 °C. Nasal solutions are handled more than injectables and are correspondingly easier to contaminate.
Long-term, frozen: Unopened powder is stable at −20 °C or colder.

On a 1 mL U-100 syringe. Check every figure against your own vial before drawing.

Water added	Concentration	Volume to draw	Units	Doses per vial
1 mL	10 mg/mL	0.1 mL	10 units	10
2 mL	5 mg/mL	0.2 mL	20 units	10
3 mL	3.333 mg/mL	0.3 mL	30 units	10
5 mL	2 mg/mL	0.5 mL	50 units	10

Descriptions of what sources report, not recommendations.

Goal	Range	Frequency	Source
Commonly described community protocol	500–1500 mcg	Once daily	Community practice

Any new neurological symptom: persistent headache, visual change, confusion, mood change or seizure activity. Seek assessment.
Any allergic response: rash, hives, facial swelling or difficulty breathing. Seek urgent care.
An injection site that becomes hot, spreading or produces pus.

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