Bioalmanac
Testosterone (TRT)
TRT · Testosterone replacement therapy · Testosterone cypionate · Testosterone enanthate
Not a peptide, and the most consequential thing on this site. Approved replacement therapy for diagnosed hypogonadism — a Schedule III controlled substance — and something that will make you infertile while you take it.
Storage
- Freeze-dried powder
- Supplied as an oil solution, not a powder. Store at room temperature, away from light.
- After mixing
- Nothing to reconstitute. A multi-dose vial is good until its expiry if the stopper is cleaned before each draw.
- Long-term, frozen
- Do not refrigerate or freeze. The oil thickens and crystals form.
Dose ranges reported in sources
Descriptions of what sources report, not recommendations.
| Goal | Range | Frequency | Source |
|---|---|---|---|
| Replacement therapy, injectable ester | 50000–100000 mcg | Weekly, or split twice weekly | Published review |
When to stop
- Chest pain, breathlessness, or leg pain and swelling. Clot symptoms. Seek emergency care.
- Haematocrit above the range your clinician set. This needs a dose change or a blood donation, not waiting.
- Breast tenderness or enlargement.
- Severe mood changes, aggression or worsening depression.
- Worsening snoring or daytime sleepiness. Sleep apnoea.
- Reduced urine flow or difficulty passing urine.
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