Bioalmanac
Thymosin Beta-4
TB4 · Tβ4 · Thymosin β4
The full 43-amino-acid protein that TB-500 is a fragment of. It reached phase 2 trials in humans. TB-500 never has.
Storage
- Freeze-dried powder
- Refrigerated at 2–8 °C, protected from light.
- After mixing
- Refrigerated at 2–8 °C. Do not freeze once mixed.
- Long-term, frozen
- Unopened powder is stable at −20 °C or colder.
Reconstitution — 10 mg vial, 5000 mcg dose
On a 1 mL U-100 syringe. Check every figure against your own vial before drawing.
| Water added | Concentration | Volume to draw | Units | Doses per vial |
|---|---|---|---|---|
| 1 mL | 10 mg/mL | 0.5 mL | 50 units | 2 |
| 2 mL | 5 mg/mL | 1 mL | 100 units | 2 |
| 3 mL | 3.333 mg/mL | — | Exceeds a 1 mL barrel | — |
| 5 mL | 2 mg/mL | — | Exceeds a 1 mL barrel | — |
Dose ranges reported in sources
Descriptions of what sources report, not recommendations.
| Goal | Range | Frequency | Source |
|---|---|---|---|
| Ophthalmic trial protocol | 100 mcg | Applied as an eye drop, twice daily | Clinical trial |
| Commonly described community protocol | 2000–5000 mcg | Twice weekly during a loading phase, then weekly | Community practice |
When to stop
- Any new lump, unexplained weight loss or unexplained persistent pain.
- Any allergic response: rash, hives, facial swelling or difficulty breathing. Seek urgent care.
- An injection site that becomes hot, spreading or produces pus.
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