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ARA-290

2 mg vial

ARA-290: a 2 mg vial

What a 2 mg vial of ARA-290 becomes once it is mixed, and what each dose reported in the sources draws to on a syringe. Every figure is arithmetic on the vial size in the heading — none of it is a recommendation, and the doses are the ones our sources describe rather than ones we picked.

Leading with

2 mg + 1 mL bacteriostatic water = 2 mg/mL

Chosen because it puts the reported doses on readable marks of a 1 mL U-100 syringe. Other volumes are perfectly valid — the dilution table further down covers them, and the concentration changes what every dose draws to.

What each reported dose draws to

At 2 mg/mL, on a 1 mL U-100 syringe. Every row names the source it came from, and a trial protocol and a community convention are not the same kind of information.

Reported doses for ARA-290, converted to syringe units for a 2 mg vial.
GoalDoseUnitsDoses in this vialSource
Phase 2 protocol for small fibre neuropathyOnce daily for 28 days · Subcutaneous4 mgMore than one vial per doseClinical trial
Commonly described community protocolOnce daily in courses of several weeks · Subcutaneous1 mg – 4 mgfrom 50 unitstop of the range needs a second vial2Community practice

CheckSome doses above need more compound than a 2 mg vial holds, so one dose spans more than one vial. A larger vial is usually the cheaper and more accurate answer than combining two.

Check every figure against the vial in front of you before drawing. Vials are filled with an overage and labels are not a guarantee. Change any of these numbers in the calculator.

If you add a different amount of water

The same 2 mg of compound, at four common volumes. More water means a larger, easier-to-measure draw of a weaker solution; less water means the opposite. The amount of compound you inject is identical in every row — only the volume carrying it changes.

Concentration and draw volume for a 2 mg vial at four water volumes.
Water addedConcentration4 mg draws to
1 mLshown above2 mg/mLExceeds a 1 mL barrel
2 mL1 mg/mLExceeds a 1 mL barrel
3 mL0.667 mg/mLExceeds a 1 mL barrel
5 mL0.4 mg/mLExceeds a 1 mL barrel

Storage

Before mixing

Refrigerated at 2–8 °C, protected from light.

After mixing

Refrigerated at 2–8 °C. Do not freeze once mixed.

Other vial sizes

The same compound, different arithmetic.

Arithmetic on the vial size named above and the doses our sources report. Nothing here is a recommendation, a protocol or medical advice, and no clinician has reviewed it. Some rows describe community practice, which is not evidence that a dose is safe or effective. Speak to a licensed healthcare provider before acting on any of it.

Sources for the doses above are listed in full on the ARA-290 profile, each with the trial or label it came from.