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10 mg vial

Cagrilintide 10 mg vial: how to reconstitute it

What a 10 mg vial of Cagrilintide becomes once it is mixed, and what each dose reported in the sources draws to on a syringe. Every figure is arithmetic on the vial size in the heading — none of it is a recommendation, and the doses are the ones our sources describe rather than ones we picked.

Leading with

10 mg + 1 mL bacteriostatic water = 10 mg/mL

Chosen because it puts the reported doses on readable marks of a 1 mL U-100 syringe. Other volumes are perfectly valid — the dilution table further down covers them, and the concentration changes what every dose draws to.

What each reported dose draws to

At 10 mg/mL, on a 1 mL U-100 syringe. Every row names the source it came from, and a trial protocol and a community convention are not the same kind of information.

Reported doses for Cagrilintide, converted to syringe units for a 10 mg vial.
GoalDoseUnitsDoses in this vialSource
Phase 2 escalation, single agentOnce weekly, escalating over several weeks · Subcutaneous300 mcg – 4.5 mg3 units – 45 units33Clinical trial
Combination with semaglutide, as studiedOnce weekly · Subcutaneous2.4 mg24 units4Clinical trial

Check every figure against the vial in front of you before drawing. Vials are filled with an overage and labels are not a guarantee. Change any of these numbers in the calculator.

Week by week

Published schedules only. Most compounds on this site have no week-by-week schedule from any source, and where that is the case this section does not appear rather than being filled in.

Reported community progression

Community practice
Reported community progression for Cagrilintide, with the syringe units for a 10 mg vial.
WeekDoseUnitsFrequency
1–2600 mcg6 unitsOnce daily
3–41.2 mg12 unitsOnce daily
5–62.4 mg24 unitsOnce daily
7–164.5 mg45 unitsOnce daily

A progression described in community sources, not a finding. No dose-ranging study establishes these steps, and the compilation they come from contained arithmetic errors in its own syringe figures — so the doses are reproduced and none of its unit conversions are.

What the whole schedule costs

Vials of this size needed to work through each step, at 1 mL per vial. The dose changes as you go, so this is not one number times a number of weeks — it is each step costed separately and added up.

Reported community progression

Vials of 10 mg needed for each step of Reported community progression.
WeekDoseDoses10 mg vials
1–2600 mcg141
3–41.2 mg142
5–62.4 mg144
7–164.5 mg7035

Reaching the end of the defined steps takes 42 vials of 10 mg over 16 weeks.

Steps whose dose exceeds this vial are marked rather than counted — at that point a larger vial is the answer, not more small ones. Nothing here accounts for a dropped vial, a held step or a dose your prescriber changes, all of which happen.

If you add a different amount of water

The same 10 mg of compound, at four common volumes. More water means a larger, easier-to-measure draw of a weaker solution; less water means the opposite. The amount of compound you inject is identical in every row — only the volume carrying it changes.

Concentration and draw volume for a 10 mg vial at four water volumes.
Water addedConcentration300 mcg draws to
1 mLshown above10 mg/mL3 units units · 0.03 mL
2 mL5 mg/mL6 units units · 0.06 mL
3 mL3.333 mg/mL9 units units · 0.09 mL
5 mL2 mg/mL15 units units · 0.15 mL

Storage

Before mixing

Refrigerated at 2–8 °C, protected from light.

After mixing

Refrigerated at 2–8 °C. Do not freeze once mixed.

Other vial sizes

The same compound, different arithmetic.

Arithmetic on the vial size named above and the doses our sources report. Nothing here is a recommendation, a protocol or medical advice, and no clinician has reviewed it. Speak to a licensed healthcare provider before acting on any of it.

Sources for the doses above are listed in full on the Cagrilintide profile, each with the trial or label it came from.