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500 mg vial

NAD+ 500 mg vial: how to reconstitute it

What a 500 mg vial of NAD+ becomes once it is mixed, and what each dose reported in the sources draws to on a syringe. Every figure is arithmetic on the vial size in the heading — none of it is a recommendation, and the doses are the ones our sources describe rather than ones we picked.

Leading with

500 mg + 1 mL bacteriostatic water = 500 mg/mL

Chosen because it puts the reported doses on readable marks of a 1 mL U-100 syringe. Other volumes are perfectly valid — the dilution table further down covers them, and the concentration changes what every dose draws to.

What each reported dose draws to

At 500 mg/mL, on a 1 mL U-100 syringe. Every row names the source it came from, and a trial protocol and a community convention are not the same kind of information.

Reported doses for NAD+, converted to syringe units for a 500 mg vial.
GoalDoseUnitsDoses in this vialSource
Subcutaneous, commonly describedDaily to a few times weekly · Subcutaneous50 mg – 100 mg10 units – 20 units10Community practice
Intravenous infusion, as offered by clinicsWeekly or less often, over several hours · Intramuscular250 mg – 1000 mgfrom 50 unitstop of the range needs a second vial2Community practice

Check every figure against the vial in front of you before drawing. Vials are filled with an overage and labels are not a guarantee. Change any of these numbers in the calculator.

Week by week

Published schedules only. Most compounds on this site have no week-by-week schedule from any source, and where that is the case this section does not appear rather than being filled in.

Reported community progression

Community practice
Reported community progression for NAD+, with the syringe units for a 500 mg vial.
WeekDoseUnitsFrequency
150 mg10 unitsOnce daily
275 mg15 unitsOnce daily
3–8100 mg20 unitsOnce daily
9–12100 mg20 unitsOnce daily
13–16100 mg20 unitsOnce daily

A progression described in community sources, not a finding. No dose-ranging study establishes these steps, and the compilation they come from contained arithmetic errors in its own syringe figures — so the doses are reproduced and none of its unit conversions are.

What the whole schedule costs

Vials of this size needed to work through each step, at 1 mL per vial. The dose changes as you go, so this is not one number times a number of weeks — it is each step costed separately and added up.

Reported community progression

Vials of 500 mg needed for each step of Reported community progression.
WeekDoseDoses500 mg vials
150 mg71
275 mg72
3–8100 mg429
9–12100 mg286
13–16100 mg286

Reaching the end of the defined steps takes 24 vials of 500 mg over 16 weeks.

Steps whose dose exceeds this vial are marked rather than counted — at that point a larger vial is the answer, not more small ones. Nothing here accounts for a dropped vial, a held step or a dose your prescriber changes, all of which happen.

If you add a different amount of water

The same 500 mg of compound, at four common volumes. More water means a larger, easier-to-measure draw of a weaker solution; less water means the opposite. The amount of compound you inject is identical in every row — only the volume carrying it changes.

Concentration and draw volume for a 500 mg vial at four water volumes.
Water addedConcentration50 mg draws to
1 mLshown above500 mg/mL10 units units · 0.1 mL
2 mL250 mg/mL20 units units · 0.2 mL
3 mL166.667 mg/mL30 units units · 0.3 mL
5 mL100 mg/mL50 units units · 0.5 mL

Storage

Before mixing

Refrigerated at 2–8 °C, protected from light.

After mixing

Refrigerated at 2–8 °C. Do not freeze once mixed.

Other vial sizes

The same compound, different arithmetic.

Arithmetic on the vial size named above and the doses our sources report. Nothing here is a recommendation, a protocol or medical advice, and no clinician has reviewed it. Some rows describe community practice, which is not evidence that a dose is safe or effective. Speak to a licensed healthcare provider before acting on any of it.

Sources for the doses above are listed in full on the NAD+ profile, each with the trial or label it came from.