A stack by coastalrower
Holding muscle through a deficit
A GLP-1 does not distinguish between fat and lean mass, and the trials report both coming off. This is the pairing people describe to protect the second, with the caveat that no trial has tested the combination.
coastalrower wrote this as a plan rather than a record. There is no dose log behind it, and nothing here says anybody followed it.
The schedule
| Compound | Dose | How often | Weeks |
|---|---|---|---|
| SemaglutideStarting dose, not a target. The approved schedule climbs over sixteen weeks and the climb is what makes it tolerable — a maintenance figure quoted without it is where people go wrong. | 500 mcg | Weekly · Mon | 1–16 |
| IpamorelinThe lean-mass half of this is an argument from mechanism, not a result. Resistance training and protein intake are the two things with actual evidence behind them here. | 200 mcg | Once daily | 1–16 |
Read thisThis is one person’s plan, published by them. We did not write it, check it, or verify that they followed it — and one person doing something is not evidence that it works or that it is safe. Every compound above links to what the published research actually says.
Report this
This page is educational. It describes what published research reports, not what you should do. Peptides discussed here are largely not approved for human use, and nothing on BioAlmanac is medical advice.
2 comments
Written by readers, not by us. Nothing here is checked, and a confident reply is not evidence.
20 Aug 2026
The summary is honest that the lean-mass half is mechanism rather than result, which is more than most versions of this manage. No trial has run the combination, so what is being protected against is real and what is doing the protecting is an argument.
25 Aug 2026
Worth flagging that 500 mcg is where the approved schedule starts and not where it ends. The titration guide on this site spends sixteen weeks getting to the maintenance figure, and the climb is what makes it tolerable — quoting the destination without the road is how most write-ups get this wrong.
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