12 mg vial
Orforglipron: a 12 mg vial
What a 12 mg vial of Orforglipron becomes once it is mixed, and what each dose reported in the sources draws to on a syringe. Every figure is arithmetic on the vial size in the heading — none of it is a recommendation, and the doses are the ones our sources describe rather than ones we picked.
Leading with
12 mg + 1 mL bacteriostatic water = 12 mg/mL
Chosen because it puts the reported doses on readable marks of a 1 mL U-100 syringe. Other volumes are perfectly valid — the dilution table further down covers them, and the concentration changes what every dose draws to.
What each reported dose draws to
At 12 mg/mL, on a 1 mL U-100 syringe. Every row names the source it came from, and a trial protocol and a community convention are not the same kind of information.
| Goal | Dose | Units | Doses in this vial | Source |
|---|---|---|---|---|
| Approved escalation for weight managementOnce daily, escalating over several months · Oral | 6 mg – 36 mg | from 50 unitstop of the range needs a second vial | 2 | Clinical trial |
Check every figure against the vial in front of you before drawing. Vials are filled with an overage and labels are not a guarantee. Change any of these numbers in the calculator.
How long a vial lasts
Vials round up, because most of a vial is not a thing you can buy. Only doses with a stated continuous frequency appear here — anything described as a course, a range or “as needed” has no honest weekly rate, so it is left out.
Approved escalation for weight management
Once daily, escalating over several months
One 12 mg vial holds 0–2 doses at this dose, which is 0–0.3 weeks of use.
| Cycle | Doses | 12 mg vials | Syringes | Bacteriostatic water |
|---|---|---|---|---|
| 8 weeks | 56 | 28–0 | 56 | 28 mL – 0 mL |
| 12 weeks | 84 | 42–0 | 84 | 42 mL – 0 mL |
| 16 weeks | 112 | 56–0 | 112 | 56 mL – 0 mL |
Syringes assume one per dose and no wastage. Water assumes each vial is mixed at 1 mL. Neither accounts for a dropped vial, a bent needle or a dose you decide to change, all of which happen.
If you add a different amount of water
The same 12 mg of compound, at four common volumes. More water means a larger, easier-to-measure draw of a weaker solution; less water means the opposite. The amount of compound you inject is identical in every row — only the volume carrying it changes.
| Water added | Concentration | 6 mg draws to |
|---|---|---|
| 1 mLshown above | 12 mg/mL | 50 units units · 0.5 mL |
| 2 mL | 6 mg/mL | 100 units units · 1 mL |
| 3 mL | 4 mg/mL | Exceeds a 1 mL barrel |
| 5 mL | 2.4 mg/mL | Exceeds a 1 mL barrel |
Storage
Before mixing
Tablets at room temperature, in the original packaging.
After mixing
Not applicable. This is a tablet.
Other vial sizes
The same compound, different arithmetic.
Arithmetic on the vial size named above and the doses our sources report. Nothing here is a recommendation, a protocol or medical advice, and no clinician has reviewed it. Speak to a licensed healthcare provider before acting on any of it.
Sources for the doses above are listed in full on the Orforglipron profile, each with the trial or label it came from.