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Orforglipron

6 mg vial

Orforglipron: a 6 mg vial

What a 6 mg vial of Orforglipron becomes once it is mixed, and what each dose reported in the sources draws to on a syringe. Every figure is arithmetic on the vial size in the heading — none of it is a recommendation, and the doses are the ones our sources describe rather than ones we picked.

Leading with

6 mg + 1 mL bacteriostatic water = 6 mg/mL

Chosen because it puts the reported doses on readable marks of a 1 mL U-100 syringe. Other volumes are perfectly valid — the dilution table further down covers them, and the concentration changes what every dose draws to.

What each reported dose draws to

At 6 mg/mL, on a 1 mL U-100 syringe. Every row names the source it came from, and a trial protocol and a community convention are not the same kind of information.

Reported doses for Orforglipron, converted to syringe units for a 6 mg vial.
GoalDoseUnitsDoses in this vialSource
Approved escalation for weight managementOnce daily, escalating over several months · Oral6 mg – 36 mgfrom 100 unitstop of the range needs a second vial1Clinical trial

Check every figure against the vial in front of you before drawing. Vials are filled with an overage and labels are not a guarantee. Change any of these numbers in the calculator.

How long a vial lasts

Vials round up, because most of a vial is not a thing you can buy. Only doses with a stated continuous frequency appear here — anything described as a course, a range or “as needed” has no honest weekly rate, so it is left out.

Approved escalation for weight management

Once daily, escalating over several months

One 6 mg vial holds 0–1 doses at this dose, which is 0–0.1 weeks of use.

Supplies for Approved escalation for weight management, by cycle length.
CycleDoses6 mg vialsSyringesBacteriostatic water
8 weeks5656–05656 mL – 0 mL
12 weeks8484–08484 mL – 0 mL
16 weeks112112–0112112 mL – 0 mL

Syringes assume one per dose and no wastage. Water assumes each vial is mixed at 1 mL. Neither accounts for a dropped vial, a bent needle or a dose you decide to change, all of which happen.

If you add a different amount of water

The same 6 mg of compound, at four common volumes. More water means a larger, easier-to-measure draw of a weaker solution; less water means the opposite. The amount of compound you inject is identical in every row — only the volume carrying it changes.

Concentration and draw volume for a 6 mg vial at four water volumes.
Water addedConcentration6 mg draws to
1 mLshown above6 mg/mL100 units units · 1 mL
2 mL3 mg/mLExceeds a 1 mL barrel
3 mL2 mg/mLExceeds a 1 mL barrel
5 mL1.2 mg/mLExceeds a 1 mL barrel

Storage

Before mixing

Tablets at room temperature, in the original packaging.

After mixing

Not applicable. This is a tablet.

Other vial sizes

The same compound, different arithmetic.

Arithmetic on the vial size named above and the doses our sources report. Nothing here is a recommendation, a protocol or medical advice, and no clinician has reviewed it. Speak to a licensed healthcare provider before acting on any of it.

Sources for the doses above are listed in full on the Orforglipron profile, each with the trial or label it came from.