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Adamax

N-Acetyl Semax Amidate variantAdamax peptide
Preclinical

Evidence

Preclinical

Typical vial

5 mg

Route

Nasal

Status

United States

What it is

A Semax derivative sold with adamantane-related branding. The least documented compound on this site, and that is saying something.

Reviewed 18 Aug 2026

Adamax is sold as a Semax derivative and is the point at which this family stops being traceable. There is no published characterisation of it — no trial in any species — and no consistent account across vendors of what it actually is.

That is a different situation from the rest of this group. Semax has Russian registration. N-acetyl Semax amidate at least has a stated structure and animal work. Adamax has a name and a set of claims.

We have written this page rather than omitting it because people buy it, and a reference that only covers what it approves of is not a reference. But the honest summary is short: nobody has established what this does, and it is not clear that any two vendors are selling the same thing.

How it works

Presumed to act as Semax does, raising BDNF and affecting dopamine and serotonin systems, purely on the basis that it is described as a Semax derivative.

No independent characterisation supports that presumption, and no study in any species has tested it.

Where a compound's structure is not publicly established, mechanism cannot be reasoned about at all. Everything in this section is inference from a name.

What it is studied for

Each entry states the evidence behind it. We do not rank indications by effectiveness — for most compounds here, that would be a claim nobody can support.

  • Cognition and focus

    Community practice

    What it is sold for.

    EvidenceNo study in any species. No published characterisation of the molecule.

Regulatory status

Last reviewed 18 Aug 2026. Positions in this category change frequently, so we date the line.

United States

Not approved anywhere and not studied anywhere. Sold as a research chemical with no published characterisation.

Identity and clearance

What the molecule is, and how long a dose stays measurable.

Molecule

Class
Described as a Semax derivative; structure not independently established

We have not stated a sequence because we could not verify one. On a page about something people put up their nose, guessing is not an option.

Dose protocols reported in sources

Displayed for reference only. Every row says where it came from, and a trial protocol and a community convention are not the same kind of information. None of this is fed into the calculator, and none of it is a recommendation.

Mixed sources

A week-by-week progression is also reported for Adamax. See it against a 5 mg vial, where the syringe units can be worked out.

Dose protocols reported in sources, with the source of each.
GoalDoseFrequencyRouteUnits, 5 mg vialSourceStart this protocol
Commonly described community protocol200 mcg – 500 mcgOnce dailyNasalThese figures are extrapolated from Semax by people who do not know what the compound is either. There is no basis for them.12–30 uCommunity practiceStart this

The doses above in syringe units, for the vial you have:

Start this copies a row into a protocol of your own, which you can then edit. Where a source gave a dose range or an ambiguous frequency, those fields arrive empty — we will not pick a number on your behalf.

CheckRows marked community practice describe what people commonly do, drawn from public discussion. They are not derived from any trial and are not evidence that a dose is safe or effective.

Safety

Reported effects, the situations that need care, and the ones that mean stop.

Read before dosing

Reported effects

  • EverythingCommunity practice

    Unknown

    No study in any species. No adverse event has ever been systematically recorded.

  • Overstimulation and disturbed sleepCommunity practice

    Anecdotally reported

When to stop

  • Any new neurological or psychiatric symptom.
  • Sleep disturbance that does not settle.
  • Nasal pain, bleeding or discharge.
  • Any allergic response: rash, hives, facial swelling or difficulty breathing. Seek urgent care.

Interactions and situations that need care

  • Buying it at allUse caution

    There is no published characterisation of this compound, no study in any species, and no way for a buyer to establish that two vendors are selling the same substance. Every other caution on this page is downstream of that.

  • Any psychiatric or neurological conditionAvoid

    An uncharacterised compound acting on the brain, in a brain already behaving unpredictably, has no upside worth the risk.

  • Pregnancy and breastfeedingAvoid

    No safety data of any kind exists, for a compound whose structure has never been publicly established. There is nothing here to weigh a risk against.

What to expect

What the sources describe over time, and how confident anyone can be about it.

No human efficacy data

HonestlyThere is no human efficacy data for this compound, so there is no evidence-based timeline to give. Any site publishing a week-by-week schedule of expected effects has invented it.

  • No study exists in any species. Not a poor one. None.
  • The structure is not publicly established, so there is no way to know whether two vendors sell the same thing.
  • Dose figures in circulation are extrapolated from Semax by people who also do not know what this is.
  • If the Semax mechanism is what interests you, Semax itself has a clinical record and this does not.

Storage and combinations

How to keep it, and what it does and does not go with.

Storage and handling

Freeze-dried powder
Refrigerated at 2–8 °C, protected from light.
After mixing
Refrigerated at 2–8 °C. Nasal solutions are handled more than injectables and are correspondingly easier to contaminate.
Long-term, frozen
Unopened powder is stable at −20 °C or colder.

Printable one-pagerHow to reconstitute a vial, step by step

With other peptides

  • Semaxcaution

    Sold as a Semax derivative, so running both risks taking the same thing twice. With no established structure, even that cannot be said with confidence.

Check this against a whole stack

Checking your vial

Research chemicals carry no manufacturing standard, so what the vial looks like is often the only quality signal available before you use it.

  • Appearance establishes nothing here

    For most peptides a collapsed cake reveals heat damage. Here there is no reference for what a correct vial looks like, because there is no published standard for what should be in it.

Vocabulary on this page

Evidence level
The category of human evidence behind a compound, from preclinical through to approved. Stated on every profile here as a category, not an adjective.
Protocol
One compound, with a dose, a frequency and a length: the plan, as opposed to what was actually taken.

The whole glossary →

Questions

Reader questions
What is actually in it?
Nobody has published a characterisation. It is described as a Semax derivative and that is as specific as the public information gets.
Why is it on this site at all?
Because people buy it, and a reference that only covers compounds it approves of is not much of a reference. The page exists to say plainly how little is known.

References

Everything on this page that came from a source, with the source.

  1. Commonly reported community protocols

    BioAlmanac editorial summary of public community sources, 2026 · Not a study

    Records dose and route patterns described in public discussion. Carries no evidential weight about safety or effect.

  2. Compiled community protocols

    BioAlmanac editorial summary of a public protocol compilation, 2026 · Not a study

    Records a week-by-week progression described on a vendor-adjacent protocol site, retrieved August 2026. Only the doses are taken from it. Its own syringe-unit conversions were checked against the vial sizes it states and several understate the volume by half, so nothing computed by that source is reproduced here — the units on this site are worked out from the vial in front of you. Carries no evidential weight about safety or effect.

Adamax compared with

Also compared with Semax, Cerebrolysin, Dihexa, N-Acetyl Semax Amidate, Adalank, Noopept.

Keep this page honest

If something here is wrong, out of date, or missing a source, tell us and we will fix it and say that we did.

Suggest a correction

This page is educational. It describes what published research reports, not what you should do. Peptides discussed here are largely not approved for human use, and nothing on BioAlmanac is medical advice. No clinician reviews these pages.

Page last updated 18 Aug 2026